Dengue is a mosquito-borne viral infection. There are four Dengue serotypes, meaning that it is possible to be infected four times.
While many Dengue infections produce only mild illness, Dengue can cause an acute flu-like illness. Occasionally this develops into a potentially lethal complication, called severe Dengue haemorrhagic fever.
Severe dengue is a leading cause of serious illness and death in some Asian and Latin American countries. It requires management by medical professionals.
Please seek Medical attention as soon as possible if you are unsure of you or your family's health condition.
There is no specific treatment or vaccine for dengue/severe dengue. Early detection of disease progression associated with severe dengue, and access to proper medical care lowers fatality rates of severe dengue to below 1%.
Dengue is found in tropical and sub-tropical climates worldwide, mostly in urban and semi-urban areas.
The global incidence of dengue has grown dramatically in recent decades. About half of the world's population is now at risk. There are an estimated 100-400 million infections each year.
Dengue prevention and control depends on effective vector control measures. Sustained community involvement can improve vector control efforts substantially.
virus is transmitted to humans through the bites of infected female
mosquitoes, primarily the Aedes aegypti mosquito.
After feeding on an dengue-infected person, the virus replicates in the mosquito midgut, before it disseminates to secondary tissues, including the salivary glands. Once infectious, the mosquito is capable of transmitting virus for the rest of its life.
Mosquitoes can become infected from people who are viremic with Dengue. This can be someone who has a symptomatic dengue infection, someone who is yet to have a symptomatic infection (they are pre-symptomatic), but also people who show no signs of illness as well (they are asymptomatic).
Human-to-mosquito transmission can occur up to 2 days before someone shows symptoms of the illness, up to 2 days after the fever has resolved.
Source : WHO
Dengue Fever Signs & Symptoms
Dengue should be suspected when a high fever (40°C/104°F) is accompanied by 2 of the following symptoms during the febrile phase:
A patient enters what is called the critical phase normally about 3-7 days after illness onset. It is at this time, when the fever is dropping (below 38°C/100°F) in the patient, that warning signs associated with severe dengue can manifest.
Severe dengue is a potentially fatal complication, due to plasma leaking, fluid accumulation, respiratory distress, severe bleeding, or organ impairment.
Warning signs that doctors should look for include:
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* Pre-Departure COVID-19 PCR Swab & Serology Test for Travellers available at AIPC, Make your appointment at Tel: 6694 1661. Click here for more details.
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Dengue Prevention & Control
Immune-mediated Cytokine Storm plays a role in Severe Dengue
- Cytokine Storms may occur in Infectious Diseases (eg SARS, Dengue etc) and lead to health complications, negative medical outcomes and/or mortality.
This is a severe immune reaction in which the body releases too many cytokines into the blood too quickly. Cytokines play an important role in normal immune responses, but having a large amount of them released in the body all at once can be harmful. A cytokine storm can occur as a result of an infection, autoimmune condition, or other disease. It may also occur after treatment with some types of immunotherapy. Signs and symptoms include high fever, inflammation (redness and swelling), and severe fatigue and nausea. Sometimes, a cytokine storm may be severe or life threatening and lead to multiple organ failure.
Up to $400 per Medisave Account per year can be used for Vaccinations under the National Adult & Childhood Immunisation Schedule - Influenza, Pneumococcal (PCV13/PPSV), Human Papillomavirus (HPV2/HPV4), Hepatitis B, Tetanus, Diphtheria & Pertussis (Tdap), Measles, Mumps & Rubella (MMR) and Chickenpox (Varicella).
AIPC is part of MOH's Swab & Go Home programme. Our clinic can carry out the COVID-19 Swab test for anyone who meets the MOH medical criteria. From 1 Jul 20, all individuals aged 13 and above, diagnosed with ARI will be COVID Swab-tested. Cost of Swab test to be borne by Ministry of Health Singapore.
AIPC is part of the National Influenza Sentinel Surveillance programme with MOH. If you have a fever of > 38 degrees with a cough, our clinic is able to test for COVID-19. For children below 12 years old with clinical diagnosis of HFMD (eg fever, oral ulcers, rash), our clinic can test for Hand Foot & Mouth Disease (The tests are for surveillance purposes only).
Vitamins & Nutrients for a Well-functioning Immune System to Protect against COVID-19 & other Viral Infections
(Ref: Nutrients. 2020 Apr 23;12(4). pii: E1181. doi: 10.3390/nu12041181 Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections Calder PC1, Carr AC2, Gombart AF3, Eggersdorfer M4.
Co-infection of COVID-19 and Dengue virus is possible
People with these symptoms may have COVID-19:
Symptom Checker – How COVID-19 Compares with Other Illnesses
Information obtained from CDC & World Health Organization
Public Health Preparedness Clinic
National University Health System Primary Care Network
Singapore Ministry of Health Chronic Disease Management Programme (CDMP)
The information provided in this website is for knowledge purposes only. It does not constitute medical advice.
Should you encounter any medical problem that you are unsure of, always consult your doctor or health care provider for assistance and medical advice.
Dr Don V H LAU Chairperson of AMDA Singapore
MBBS (Monash), B.Med.Sc.(Hons) (Monash), Grad.Dip.Derm.(Wales,UK)
AMDA International Peace Clinic is a part of AMDA (Association of Medical Doctors of Asia). We are part of the network of AMDA Peace Clinics & Friendship Hospitals around the world. We participate in AMDA's worldwide Emergency Disaster Aid Relief missions, Social Development projects and Vaccination programmes.
AMDA, founded in 1984 has carried out more than 200 medical missions, contributing medical expertise and supplies in 65 countries over the last 36 years. AMDA holds General Consultative Status with the United Nations Economic & Social Council (UN ECOSOC) since 1995.
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MBBS (Monash), B Med Sc (Hons) (Monash), Dip Pract Derm (Wales, UK)
Chairperson of AMDA Singapore
Doctor of Chiropractic Southern California University of Health Science
The Chiropractic Association Singapore, Japan Chiropractic Register, American Chiropractic Association, California Chiropractic Association
Physiotherapy-trained NBCE The National Board of Chiropractic Examiners
Dr Lee Sao Bing – Opthalmologist (in-house Specialist)
MBBS, MMed(Ophth), FRCSEd(Ophth), MD, FAMS
Dr Pang Yoke Teen – ENT (Visiting Consultant)
FRCS (ORL), FRCS(EDIN), (FRCSGLASG), FAMS, MBBS
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AMDA International Peace Clinic dedicates part of our profits to AMDA's Worldwide Emergency Disaster Aid Relief missions, Social Development projects & Vaccination programmes.
Founder & President of AMDA - Association of Medical Doctors of Asia
INTERVIEW of Dr Shigeru Suganami, Founder & President of AMDA - Association of Medical Doctors of Asia, Medical Director of AMDA International Peace Clinic with Mr Ando of JPlus Magazine Singapore (in Japanese / Part 1 of 8)
INTERVIEW with Dr Shigeru Suganami, Medical Director of AMDA International Peace Clinic (in Japanese / Part 2 of 8)
INTERVIEW with Dr Shigeru Suganami, Medical Director of AMDA International Peace Clinic (in Japanese / Part 3 of 8)
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